Short answer: Itโs never too late. Skin continues to remodel at every ageโyou just need a steadier, barrierโfirst approach.
Whatโs happening at the cell level:
- Slower turnover: keratinocytes shed less efficiently โ dullness and rough texture.
- Collagen & elastin decline: fibroblast activity slows and UVโdriven enzymes (MMPs) break down fibers โ laxity and fine lines.
- Oxidative stress & glycation: ROS and sugarโlinked AGEs stiffen collagen โ a crepier look.
- Barrier lipid shifts: fewer ceramides/fatty acids โ more TEWL and sensitivity.
Build a consistent routine:
- Cleanser โ gentle cream or oil cleanse at night; splash or mild gel in AM.
- Toner โ hydrating/soothing mist or essence.
- Treatments โ AM: antioxidants (e.g., vitamin C), niacinamide, peptides. PM: a retinoid 2โ3ร/week; peptides or barrier serum on offโnights; gentle exfoliation ~1ร/week if tolerated.
- Moisturizer โ ceramideโrich cream; finish with SPF 30โ50 every morning.
Lifestyle assists: daily sunscreen reโapplication, neck & chest application, light massage, proteinโrich diet, resistance training, good sleep, stress care, and a bedside humidifier.